Correlation between disease phenotype and genetic heterogeneity in rheumatoid arthritis.

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Correlation between disease phenotype and genetic heterogeneity in rheumatoid arthritis.

RA is a heterogeneous group of disorders characterized by variations in clinical manifestations, disease course, and probably response to therapeutic interventions. We have addressed the question whether genetically and potentially etiologically more homogeneous subgroups of RA patients can be defined based upon the expression of the RA-linked sequence motif in the third hypervariable region of...

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Genetic contribution to susceptibility and disease phenotype in rheumatoid arthritis

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1995

ISSN: 0021-9738

DOI: 10.1172/jci117900